Research Articles
The Biomarker Toolkit: A Step-by-Step Guide for Cancer Research and Clinical Success
This comprehensive guide provides researchers, scientists, and drug development professionals with a practical framework for successful cancer biomarker development.
Bayesian Adaptive Master Protocols: The Future of Efficient & Adaptive Clinical Trial Design
This article provides a comprehensive guide to Bayesian adaptive methods within master protocol trials for drug development professionals.
Cancer Immunoediting Explained: From Immune Surveillance Principles to Immunotherapy Application
This article provides a comprehensive examination of the core principles of cancer immunoediting and immune surveillance, tailored for researchers and drug development professionals.
BMI-1 Inhibitors: Targeting the Core of Cancer Stemness for Next-Generation Therapy
This article provides a comprehensive overview of BMI-1 (B-cell-specific Moloney murine leukemia virus integration site 1) as a master regulator of cancer stem cell (CSC) stemness and a promising therapeutic...
BLCAP Gene as a Predictive Biomarker for Anti-CTLA-4 Immunotherapy Response: A Research and Development Guide
This article provides a comprehensive examination of the Bladder Cancer-Associated Protein (BLCAP) gene as a novel biomarker for predicting patient response to CTLA-4 checkpoint inhibitor therapy.
BCMA-Targeted Therapies in Multiple Myeloma: A Comprehensive 2024 Review of CAR-T Efficacy, BiTE Safety, and Clinical Implications
This article provides a detailed comparative analysis of B-cell maturation antigen (BCMA)-targeted immunotherapies for relapsed/refractory multiple myeloma, focusing on chimeric antigen receptor T-cell (CAR-T) therapies and bispecific T-cell engagers (BiTEs).
BCL2, FGFR3, and YAP1 as Predictive Biomarkers for Immunotherapy Response: A 2024 Research Review
This article provides a comprehensive review for researchers and drug development professionals on the emerging predictive roles of BCL2, FGFR3, and YAP1 in immunotherapy outcomes.
Automated Image Analysis for Cancer Stem Cell Biomarker Quantification: From Protocols to Clinical Translation
This article provides a comprehensive guide for researchers and drug development professionals on implementing automated image analysis for quantifying Cancer Stem Cell (CSC) biomarkers.
Disrupting the Fortress: Cutting-Edge Strategies to Target the Adenosine Pathway in the Tumor Microenvironment for Cancer Immunotherapy
This article provides a comprehensive overview of the latest advances in targeting the immunosuppressive adenosine pathway within the tumor microenvironment (TME).
The Ultimate Guide to Aldefluor Assay: Protocol, Optimization, and Clinical Applications in Stem Cell & Cancer Research
This comprehensive guide details the Aldefluor assay for detecting ALDH enzymatic activity, a key marker for stem and progenitor cells.